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Macular Pigment Optical Density (MPOD):
A New Desktop Instrument for Measuring Macular Pigment Optical Density
(Van Der Veen, et al. - Ophthalmology and Physiological Optics 2009)
• MPOD was measured with the QuantifEye device and the method demonstrated good repeatability with (r = 97) and the data are comparable with retinal reflectometry. (r = .78)
Desktop Macular Pigment Optical Density Measurement: A New approach based on Heterochromatic FlickerPhotometry
(Berendschot, et. al. - Eye 2011)
• We found low agreement between test and retest measurements with Macuscope
• We found high agreement between test and retest measurements of QuantifEye (0.02 ± 0.18) and the fundus reflectance method
The Value of Measurement of Macular Carotenoid Pigment Optical Densities and Distributions in Age-Related Macular Degeneration
(Bernstein, et. al. – Vision Research 50, 2010)
• The antioxidant and blue light filtering functions of lutein and zeaxanthin have an impact upon eye health beyond just decreasing the risk of agerelated eye disease. Macular pigment has also been shown to influence visual function and comfort
• The panel concluded that it might be possible to identify individuals at reduced, medium, and elevated risk for age-related eye disease based on high, medium, and low central MPOD levels
• The panel members agreed that a central MPOD below 0.2 d.u. should be considered low, between 0.2 d.u. and 0.5 d.u. is mid-range, and levels above 0.5 d.u. as high
• Approximately 43% of the US population has a central MPOD below 0.2 d.u.
• Approximately 78% of the US population has a central MPOD below 0.5 d.u
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